| Skyla | Woman | American Names |
| Skylar | Unisex | American Names |
| Slash | Unisex | American Names |
| Slate | Man | American Names |
| Soctayvian | Man | American Names |
| Sojourner | Unisex | American Names |
| Sokka | Man | American Names |
| Sondra | Woman | American Names |
| Sonny | Man | American Names |
| Sontee | Unisex | American Names |
| Sookie | Woman | American Names |
| Sophilia | Woman | American Names |
| Sorina | Woman | American Names |
| Sosie | Woman | American Names |
| Southern | Unisex | American Names |
| Spainleigh | Woman | American Names |
| Spanky | Man | American Names |
| Sparkle | Woman | American Names |
| Spicer | Man | American Names |
| Spike | Man | American Names |