| Santino | Man | Italian Names |
| Santuzza | Woman | Italian Names |
| Sarafina | Woman | Italian Names |
| Saveria | Woman | Italian Names |
| Saverio | Man | Italian Names |
| Scholastica | Woman | Italian Names |
| Scianna | Unisex | Italian Names |
| Sergio | Man | Italian Names |
| Sienna | Woman | Italian Names |
| Sinatra | Man | Italian Names |
| Sofonisba | Woman | Italian Names |
| Speranza | Woman | Italian Names |
| Stamatina | Woman | Italian Names |
| Stefania | Woman | Italian Names |
| Stefano | Man | Italian Names |
| Tanaquil | Woman | Italian Names |
| Telma | Woman | Italian Names |
| Teo | Man | Italian Names |
| Teofila | Woman | Italian Names |
| Teresina | Woman | Italian Names |