| Senona | Woman | Spanish Names |
| Senorita | Woman | Spanish Names |
| Sereno | Man | Spanish Names |
| Serrano | Unisex | Spanish Names |
| Severo | Man | Spanish Names |
| Sevilla | Unisex | Spanish Names |
| Sibila | Woman | Spanish Names |
| Sierra | Woman | Spanish Names |
| Silvino | Man | Spanish Names |
| Simona | Woman | Spanish Names |
| Sinforoso | Man | Spanish Names |
| Sirena | Woman | Spanish Names |
| Sixto | Man | Spanish Names |
| Socorro | Woman | Spanish Names |
| Sofia | Woman | Spanish Names |
| Sofranór | Man | Spanish Names |
| Sofronia | Woman | Spanish Names |
| Sol | Unisex | Spanish Names |
| Sola | Woman | Spanish Names |
| Soledad | Woman | Spanish Names |